"Long long ago, in a laboratory far far away, scientists figured out that chimpanzees have 24 chromosomes in their sperms and eggs, whereas humans only have 23. Therefore, these great scientists theorized that two of our chromosomes might have fused together sometime in the recent past (aka millions of years ago).
As you might have guessed, all three predictions have been verified. While, as always, it's impossible to prove that an all-powerful being didn't create the evidence to trick us, the reasonable explanation is that humans and chimps share a common ancestor.
For a more detailed analysis, see Comparison of the Human and Great Ape Chromosomes as Evidence for Common Ancestry.
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